We develop 3D plane-wave migration in tilted coordinates for anisotropic media. We transform the recorded surface data to plane-wave data by slant-stack processing. Both the source plane-wave and its corresponding slant-stacked data are extrapolated into the subsurface within a tilted coordinates system whose direction depends on the propagation direction of the plane-wave. Images are generated by cross-correlating these two wavefields. A real dataset from Gulf of Mexico shows that this technique can image steeply dipping salt flanks and faults, even though the one-way wave equation operator is used for the wavefield extrapolation.